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The Effectiveness of Afatinib in a Patient with Advanced Lung Adenocarcinoma Harboring Rare G719X and S768I Mutations

The uncommon mutations in the EGFR (the epithelial growth factor receptor) gene include a heterogeneous group of genomic alterations within exons 18-21. The clinical response of patients with such mutations to EGFR tyrosine kinase inhibitor (EGFR-TKI) treatment, however, remains unclear. We herein r...

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Detalles Bibliográficos
Autores principales: Watanabe, Masahiro, Oizumi, Satoshi, Kiuchi, Shizuka, Yamada, Noriyuki, Yokouchi, Hiroshi, Fukumoto, Shinichi, Harada, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919859/
https://www.ncbi.nlm.nih.gov/pubmed/29225262
http://dx.doi.org/10.2169/internalmedicine.9565-17