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NF-κB promotes the stem-like properties of leukemia cells by activation of LIN28B

AIM: To examine whether nuclear factor kappa B (NF-κB) activity regulates LIN28B expression and their roles in leukemia stem cell (LSC)-like properties. METHODS: We used pharmacological inhibitor and cell viability assays to examine the relation between NF-κB and LIN28B. Western blot and qRT-PCR was...

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Detalles Bibliográficos
Autores principales: Zhou, Jianbiao, Chooi, Jing-Yuan, Ching, Ying Qing, Quah, Jessie Yiying, Toh, Sabrina Hui-Min, Ng, Yvonne, Tan, Tuan Zea, Chng, Wee-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919888/
https://www.ncbi.nlm.nih.gov/pubmed/29707103
http://dx.doi.org/10.4252/wjsc.v10.i4.34