Increased transforming growth factor beta (TGF-β) and pSMAD3 signaling in a Murine Model for Contrast Induced Kidney Injury

We tested the hypothesis that post-contrast acute kidney injury (PC-AKI) occurs due to increase in transforming growth factor beta (Tgf-β) and pSMAD3 signaling in a murine model of PC-AKI. Mice had nephrectomy performed and twenty-eight days later, 100-μL of radio-contrast (Vispaque 320) or saline w...

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Detalles Bibliográficos
Autores principales: Kilari, Sreenivasulu, Yang, Binxia, Sharma, Amit, McCall, Deborah L., Misra, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919895/
https://www.ncbi.nlm.nih.gov/pubmed/29700311
http://dx.doi.org/10.1038/s41598-018-24340-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919895/
https://www.ncbi.nlm.nih.gov/pubmed/29700311
http://dx.doi.org/10.1038/s41598-018-24340-z

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