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16 kDa vasoinhibin binds to integrin alpha5 beta1 on endothelial cells to induce apoptosis

Many functions of vasoinhibins have been reported, but its receptor has not been clarified yet. Vasoinhibins, 11–18 kDa N-terminal fragments of prolactin, have anti-angiogenic activity and act on endothelial cells to induce apoptosis and to inhibit migration and proliferation, which are opposite to...

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Detalles Bibliográficos
Autores principales: Morohoshi, Kazunori, Mochinaga, Ryo, Watanabe, Tsukasa, Nakajima, Ryojun, Harigaya, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919937/
https://www.ncbi.nlm.nih.gov/pubmed/29622663
http://dx.doi.org/10.1530/EC-18-0116