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Decrease of cocaine, but not heroin, self-administration and relapse by the tyrosine kinase inhibitor masitinib in male Sprague Dawley rats

RATIONALE: Accumulating evidence shows that cocaine, and also heroin, influence several tyrosine kinases, expressed in neurons and in non-neuronal populations such as microglia, astrocytes and mast-cells. Drug-induced activation of mast cells both triggers inflammatory processes in the brain mediate...

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Detalles Bibliográficos
Autores principales: Belin-Rauscent, A., Lacoste, J., Hermine, O., Moussy, A., Everitt, B. J., Belin, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920000/
https://www.ncbi.nlm.nih.gov/pubmed/29520592
http://dx.doi.org/10.1007/s00213-018-4865-0