TIMP3 Overexpression Improves the Sensitivity of Osteosarcoma to Cisplatin by Reducing IL-6 Production

Osteosarcoma is the most common bone cancer in children and adolescents. Tissue inhibitors of metalloproteinases (TIMPs)-3 inhibit matrix metalloproteinases to limit extracellular matrix degradation. Cisplatin is a widely used chemotherapeutic drug used to cure osteosarcoma. Interleukin (IL)-6 and T...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Xiu-guo, Mo, Hui-min, Liu, Xu-qiang, Li, Yan, Du, Lin, Qiao, Han, Fan, Qi-ming, Zhao, Jie, Zhang, Shu-hong, Tang, Ting-ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920027/
https://www.ncbi.nlm.nih.gov/pubmed/29731768
http://dx.doi.org/10.3389/fgene.2018.00135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920027/
https://www.ncbi.nlm.nih.gov/pubmed/29731768
http://dx.doi.org/10.3389/fgene.2018.00135

Ejemplares similares