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TIMP3 Overexpression Improves the Sensitivity of Osteosarcoma to Cisplatin by Reducing IL-6 Production

Osteosarcoma is the most common bone cancer in children and adolescents. Tissue inhibitors of metalloproteinases (TIMPs)-3 inhibit matrix metalloproteinases to limit extracellular matrix degradation. Cisplatin is a widely used chemotherapeutic drug used to cure osteosarcoma. Interleukin (IL)-6 and T...

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Detalles Bibliográficos
Autores principales:	Han, Xiu-guo, Mo, Hui-min, Liu, Xu-qiang, Li, Yan, Du, Lin, Qiao, Han, Fan, Qi-ming, Zhao, Jie, Zhang, Shu-hong, Tang, Ting-ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920027/ https://www.ncbi.nlm.nih.gov/pubmed/29731768 http://dx.doi.org/10.3389/fgene.2018.00135

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