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The Neuroprotection of Low-Dose Morphine in Cellular and Animal Models of Parkinson’s Disease Through Ameliorating Endoplasmic Reticulum (ER) Stress and Activating Autophagy

Parkinson’s disease (PD) is a common neurodegenerative disease characterized the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Brain endogenous morphine biosynthesis was reported to be impaired in PD patients and exogenous morphine attenuated 6-hydroxydop...

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Detalles Bibliográficos
Autores principales: Wang, Bing, Su, Cun-Jin, Liu, Teng-Teng, Zhou, Yan, Feng, Yu, Huang, Ya, Liu, Xu, Wang, Zhi-Hong, Chen, Li-Hua, Luo, Wei-Feng, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920031/
https://www.ncbi.nlm.nih.gov/pubmed/29731707
http://dx.doi.org/10.3389/fnmol.2018.00120