Antisense Phosphorodiamidate Morpholino Oligomers as Novel Antiviral Compounds

Phosphorodiamidate morpholino oligomers (PMO) are short single-stranded DNA analogs that are built upon a backbone of morpholine rings connected by phosphorodiamidate linkages. As uncharged nucleic acid analogs, PMO bind to complementary sequences of target mRNA by Watson–Crick base pairing to block...

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Detalles Bibliográficos
Autores principales: Nan, Yuchen, Zhang, Yan-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920040/
https://www.ncbi.nlm.nih.gov/pubmed/29731743
http://dx.doi.org/10.3389/fmicb.2018.00750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920040/
https://www.ncbi.nlm.nih.gov/pubmed/29731743
http://dx.doi.org/10.3389/fmicb.2018.00750

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