KH176 Safeguards Mitochondrial Diseased Cells from Redox Stress-Induced Cell Death by Interacting with the Thioredoxin System/Peroxiredoxin Enzyme Machinery

A deficient activity of one or more of the mitochondrial oxidative phosphorylation (OXPHOS) enzyme complexes leads to devastating diseases, with high unmet medical needs. Mitochondria, and more specifically the OXPHOS system, are the main cellular production sites of Reactive Oxygen Species (ROS). I...

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Detalles Bibliográficos
Autores principales: Beyrath, Julien, Pellegrini, Mina, Renkema, Herma, Houben, Lisanne, Pecheritsyna, Svetlana, van Zandvoort, Peter, van den Broek, Petra, Bekel, Akkiz, Eftekhari, Pierre, Smeitink, Jan A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920042/
https://www.ncbi.nlm.nih.gov/pubmed/29700325
http://dx.doi.org/10.1038/s41598-018-24900-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920042/
https://www.ncbi.nlm.nih.gov/pubmed/29700325
http://dx.doi.org/10.1038/s41598-018-24900-3

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