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Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics

The 60 kDa heat shock protein (Hsp60) is classically known as a mitochondrial chaperonin protein working together with co-chaperonin 10 kDa heat shock protein (Hsp10). This chaperonin complex is essential for folding proteins newly imported into mitochondria. However, Hsp60, and/or Hsp10 have also b...

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Detalles Bibliográficos
Autores principales: Meng, Qianli, Li, Bingbing X., Xiao, Xiangshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920047/
https://www.ncbi.nlm.nih.gov/pubmed/29732373
http://dx.doi.org/10.3389/fmolb.2018.00035