RTS,S/AS01 malaria vaccine mismatch observed among Plasmodium falciparum isolates from southern and central Africa and globally

The RTS,S/AS01 malaria vaccine encompasses the central repeats and C-terminal of Plasmodium falciparum circumsporozoite protein (PfCSP). Although no Phase II clinical trial studies observed evidence of strain-specific immunity, recent studies show a decrease in vaccine efficacy against non-vaccine s...

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Detalles Bibliográficos
Autores principales: Pringle, Julia C., Carpi, Giovanna, Almagro-Garcia, Jacob, Zhu, Sha Joe, Kobayashi, Tamaki, Mulenga, Modest, Bobanga, Thierry, Chaponda, Mike, Moss, William J., Norris, Douglas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920075/
https://www.ncbi.nlm.nih.gov/pubmed/29700348
http://dx.doi.org/10.1038/s41598-018-24585-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920075/
https://www.ncbi.nlm.nih.gov/pubmed/29700348
http://dx.doi.org/10.1038/s41598-018-24585-8

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