The therapeutic effect of miR-125b is enhanced by the prostaglandin endoperoxide synthase 2/cyclooxygenase 2 blockade and hampers ETS1 in the context of the microenvironment of bone metastasis

Bone is the most common site for breast cancer spread. In the pro-metastatic cell line 1833, derived from MDA-MB-231 breast adenocarcinoma cells, both hypoxia and hepatocyte growth factor (HGF) influence the effect of miR-125b on ETS proto-oncogene 1 transcription factor (ETS1). The effect of hypoxi...

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Detalles Bibliográficos
Autores principales: Maroni, Paola, Bendinelli, Paola, Matteucci, Emanuela, Desiderio, Maria Alfonsina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920088/
https://www.ncbi.nlm.nih.gov/pubmed/29700305
http://dx.doi.org/10.1038/s41419-018-0499-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920088/
https://www.ncbi.nlm.nih.gov/pubmed/29700305
http://dx.doi.org/10.1038/s41419-018-0499-8

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