Cargando…

The therapeutic effect of miR-125b is enhanced by the prostaglandin endoperoxide synthase 2/cyclooxygenase 2 blockade and hampers ETS1 in the context of the microenvironment of bone metastasis

Bone is the most common site for breast cancer spread. In the pro-metastatic cell line 1833, derived from MDA-MB-231 breast adenocarcinoma cells, both hypoxia and hepatocyte growth factor (HGF) influence the effect of miR-125b on ETS proto-oncogene 1 transcription factor (ETS1). The effect of hypoxi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maroni, Paola, Bendinelli, Paola, Matteucci, Emanuela, Desiderio, Maria Alfonsina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920088/ https://www.ncbi.nlm.nih.gov/pubmed/29700305 http://dx.doi.org/10.1038/s41419-018-0499-8

Ejemplares similares

Cell and Signal Components of the Microenvironment of Bone Metastasis Are Affected by Hypoxia
por: Bendinelli, Paola, et al.
Publicado: (2016)

Microenvironment Stimuli HGF and Hypoxia Differently Affected miR-125b and Ets-1 Function with Opposite Effects on the Invasiveness of Bone Metastatic Cells: A Comparison with Breast Carcinoma Cells
por: Matteucci, Emanuela, et al.
Publicado: (2018)

Bone Metastasis Phenotype and Growth Undergo Regulation by Micro-Environment Stimuli: Efficacy of Early Therapy with HGF or TGFβ1-Type I Receptor Blockade
por: Bendinelli, Paola, et al.
Publicado: (2019)

HGF and TGFβ1 differently influenced Wwox regulatory function on Twist program for mesenchymal-epithelial transition in bone metastatic versus parental breast carcinoma cells
por: Bendinelli, Paola, et al.
Publicado: (2015)

Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors
por: Maroni, Paola, et al.
Publicado: (2017)

Epigenetic regulation of HGF/Met receptor axis is critical for the outgrowth of bone metastasis from breast carcinoma
por: Bendinelli, Paola, et al.
Publicado: (2017)

Retraction Note: HGF and TGFβ1 differently influenced Wwox regulatory function on Twist program for mesenchymal-epithelial transition in bone metastatic versus parental breast carcinoma cells
por: Bendinelli, Paola, et al.
Publicado: (2020)

Retraction Note to: Epigenetic regulation of HGF/Met receptor axis is critical for the outgrowth of bone metastasis from breast carcinoma
por: Bendinelli, Paola, et al.
Publicado: (2022)

The Autophagic Process Occurs in Human Bone Metastasis and Implicates Molecular Mechanisms Differently Affected by Rab5a in the Early and Late Stages
por: Maroni, Paola, et al.
Publicado: (2016)

Osteolytic bone metastasis is hampered by impinging on the interplay among autophagy, anoikis and ossification
por: Maroni, P, et al.
Publicado: (2014)

Retraction Note: Osteolytic bone metastasis is hampered by impinging on the interplay among autophagy, anoikis and ossification
por: Maroni, P., et al.
Publicado: (2022)

Common Variants of the Prostaglandin-Endoperoxide Synthase 2 Gene and Hepatocellular Carcinoma Susceptibility
por: Li, Hong-guang, et al.
Publicado: (2015)

Post-translational modifications of prostaglandin-endoperoxide synthase 2 in colorectal cancer: An update
por: Jaén, Rafael I, et al.
Publicado: (2018)

High SPARC Expression Starting from Dysplasia, Associated with Breast Carcinoma, Is Predictive for Bone Metastasis without Enhancement of Plasma Levels
por: Maroni, Paola, et al.
Publicado: (2015)

In vitro functional characterization of prostaglandin-endoperoxide synthase 2 during chondrocyte hypertrophic differentiation
por: Li, Na, et al.
Publicado: (2016)

The Role of Prostaglandin-Endoperoxide Synthase-2 in Chemoresistance of Non-Small Cell Lung Cancer
por: Lin, Xiao-mian, et al.
Publicado: (2019)

Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2
por: Trostchansky, Andrés, et al.
Publicado: (2011)

Prognostic Value of Prostaglandin-endoperoxide Synthase 2 Polymorphisms in Prostate Cancer Recurrence after Radical Prostatectomy
por: Lee, Cheng-Hsueh, et al.
Publicado: (2016)

Modulation of the prostaglandin-endoperoxide synthase 2 gene expression by variant haplotypes: influence of the 3′-untranslated region
por: Piranda, D.N., et al.
Publicado: (2017)

Prognostic Significance of Prostaglandin-Endoperoxide Synthase-2 Expressions in Human Breast Carcinoma: A Multiomic Approach
por: Saindane, Madhuri, et al.
Publicado: (2020)

Effects of selenium intake on the expression of prostaglandin-endoperoxide synthase 2 (cyclooxygenase-2) and matrix metallopeptidase-9 genes in the coronary artery disease: Selenegene study, a double-blind randomized controlled trial
por: Gharipour, Mojgan, et al.
Publicado: (2021)

Human parathyroid hormone fragment stimulates the de novo synthesis of prostaglandin endoperoxide synthase in chick calvaria
por: Yang, Chin-Yuh, et al.
Publicado: (1993)

The Bradykinin System Contributes to the Regulation of Prostaglandin-Endoperoxide Synthase 2 Expression in Human Amnion Fibroblasts: Implications for Term and Preterm Birth
por: Ni, Xiao-tian, et al.
Publicado: (2022)

Characterization of an AM404 Analogue, N-(3-Hydroxyphenyl)arachidonoylamide, as a Substrate and Inactivator of Prostaglandin Endoperoxide Synthase
por: Turman, Melissa V., et al.
Publicado: (2009)

Studies on Prostaglandin-Endoperoxide Synthase 1: Lower Levels in Schizophrenia and After Treatment with Antipsychotic Drugs in Conjunction with Aspirin
por: Dean, Brian, et al.
Publicado: (2017)

Assessment of Prostaglandin-Endoperoxide Synthase 2 and Versican gene expression profile from the cumulus cells: association with better in vitro fertilization outcomes
por: Ocampo, Azucena, et al.
Publicado: (2018)

Epidermal growth factor receptor (EGFR) and prostaglandin-endoperoxide synthase 2 (PTGS2) are prognostic biomarkers for patients with resected colorectal cancer liver metastases
por: Goos, J A C M, et al.
Publicado: (2014)

Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer
por: Cox, D G, et al.
Publicado: (2004)

miR-103 Promotes Neurite Outgrowth and Suppresses Cells Apoptosis by Targeting Prostaglandin-Endoperoxide Synthase 2 in Cellular Models of Alzheimer’s Disease
por: Yang, Hui, et al.
Publicado: (2018)

Expression and cellular localization of cyclooxygenases and prostaglandin E synthases in the hemorrhagic brain
por: Wu, Tao, et al.
Publicado: (2011)

A fluorescence microscopy method for quantifying levels of prostaglandin endoperoxide H synthase-1 and CD-41 in MEG-01 cells
por: Franks, Douglas J, et al.
Publicado: (2001)

Prostaglandin-endoperoxide synthase 2 (PTGS2) gene expression and its association with genes regulating the VEGF signaling pathway in head and neck squamous cell carcinoma
por: Kamal, Mehta Vedant, et al.
Publicado: (2023)

Cyclooxygenase and Prostaglandin in Cancer
por: Kim, Jong-Woo
Publicado: (2012)

Renal Effects of Prostaglandins and Cyclooxygenase-2 Inhibitors
por: Kim, Gheun-Ho
Publicado: (2008)

A polymorphism in the 3' untranslated region of the gene encoding prostaglandin endoperoxide synthase 2 is not associated with an increase in breast cancer risk: a nested case-control study
por: Cox, David G, et al.
Publicado: (2007)

Physiology and pathophysiology of cyclooxygenase-2 and prostaglandin E2 in the kidney
por: Nørregaard, Rikke, et al.
Publicado: (2015)

Bone, a Secondary Growth Site of Breast and Prostate Carcinomas: Role of Osteocytes
por: Maroni, Paola, et al.
Publicado: (2020)

Microsomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E(2)
por: Sampey, Annaleise V, et al.
Publicado: (2005)

Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1
por: Sasaki, Yuka, et al.
Publicado: (2015)

Marine Terpenic Endoperoxides
por: Torres-García, Irene, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lusrs3rhsekovn96o96iqlrsql