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YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD

Yes-associated protein 1 (YAP1) contributes to the development of multiple tumors, but the mechanism underlying YAP1 deregulation in non-small cell lung cancer (NSCLC) remains unclear. By performing immunohistochemistry (IHC) assays, we found that YAP1 was significantly upregulated in NSCLC compared...

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Detalles Bibliográficos
Autores principales: Yu, Mengxue, Chen, Yingzhun, Li, Xuelian, Yang, Rui, Zhang, Lijia, Huangfu, Longtao, Zheng, Nan, Zhao, Xiaoguang, Lv, Lifang, Hong, Yaozhen, Liang, Haihai, Shan, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920099/
https://www.ncbi.nlm.nih.gov/pubmed/29700328
http://dx.doi.org/10.1038/s41419-018-0515-z