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Differential regulation of AKT1 contributes to survival and proliferation in hepatocellular carcinoma cells by mediating Notch1 expression

The RAC serine/threonine-protein kinase (AKT) family of serine/threonine protein kinases, particularly the AKT1 isoform, has been identified abnormally expressed in hepatocellular carcinoma (HCC) cells, and is highly associated with cell behavior, including proliferation, survival, metabolism, and t...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Liang, Jun, Liu, Shihai, Song, Shanai, Guo, Wenxuan, Shen, Fangzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920202/
https://www.ncbi.nlm.nih.gov/pubmed/29725418
http://dx.doi.org/10.3892/ol.2018.8193