Spatial separation between replisome‐ and template‐induced replication stress signaling

Polymerase‐blocking DNA lesions are thought to elicit a checkpoint response via accumulation of single‐stranded DNA at stalled replication forks. However, as an alternative to persistent fork stalling, re‐priming downstream of lesions can give rise to daughter‐strand gaps behind replication forks. W...

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Detalles Bibliográficos
Autores principales: García‐Rodríguez, Néstor, Morawska, Magdalena, Wong, Ronald P, Daigaku, Yasukazu, Ulrich, Helle D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920239/
https://www.ncbi.nlm.nih.gov/pubmed/29581097
http://dx.doi.org/10.15252/embj.201798369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920239/
https://www.ncbi.nlm.nih.gov/pubmed/29581097
http://dx.doi.org/10.15252/embj.201798369

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