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Alterations in sperm DNA methylation, non-coding RNA expression, and histone retention mediate vinclozolin-induced epigenetic transgenerational inheritance of disease

Epigenetic transgenerational inheritance of disease and phenotypic variation can be induced by several toxicants, such as vinclozolin. This phenomenon can involve DNA methylation, non-coding RNA (ncRNA) and histone retention, and/or modification in the germline (e.g. sperm). These different epigenet...

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Detalles Bibliográficos
Autores principales: Ben Maamar, Millissia, Sadler-Riggleman, Ingrid, Beck, Daniel, McBirney, Margaux, Nilsson, Eric, Klukovich, Rachel, Xie, Yeming, Tang, Chong, Yan, Wei, Skinner, Michael K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920293/
https://www.ncbi.nlm.nih.gov/pubmed/29732173
http://dx.doi.org/10.1093/eep/dvy010