The siRNA silencing of DcR3 expression induces Fas ligand-mediated apoptosis in HepG2 cells

Dysfunctional Fas ligand (FasL) may inhibit the apoptosis of tumor cells. FasL contains two receptors, Fas and Decoy Receptor 3 (DcR3). DcR3 competitively binds to FasL over Fas, resulting in the inhibition of FasL-mediated apoptosis. Therefore, it was suggested that the downregulation of DcR3 expre...

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Detalles Bibliográficos
Autores principales: Zhao, Tuanjie, Xu, Yingchen, Ren, Shulin, Liang, Chaojie, Zhou, Xiaona, Wu, Jixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920343/
https://www.ncbi.nlm.nih.gov/pubmed/29725377
http://dx.doi.org/10.3892/etm.2018.5964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920343/
https://www.ncbi.nlm.nih.gov/pubmed/29725377
http://dx.doi.org/10.3892/etm.2018.5964

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