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Uncovering the heterogeneous genetic variations in two insulin-expressing tumors in a patient with MEN1

Multiple endocrine neoplasia type 1 (MEN1) is associated with a heterozygous inherited mutation of the menin 1 (MEN1) gene; however, the molecular pathogenesis remains to be fully elucidated. In the present study, whole exome sequencing was performed on two pancreatic neuroendocrine tumors (PNETs),...

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Detalles Bibliográficos
Autores principales: Wang, Zai, Liu, Liguo, Luo, Jie, Guo, Jing, Zhai, Min, Zhang, Wenjian, Yang, Zhiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920406/
https://www.ncbi.nlm.nih.gov/pubmed/29725435
http://dx.doi.org/10.3892/ol.2018.8184