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Telocinobufagin inhibits the epithelial-mesenchymal transition of breast cancer cells through the phosphoinositide 3-kinase/protein kinase B/extracellular signal-regulated kinase/Snail signaling pathway

Telocinobufagin (TBG), an active ingredient of Venenumbufonis, exhibits an immunomodulatory activity. However, its antimetastatic activity in breast cancer remains unknown. The present study investigated whether TBG prevents breast cancer metastasis and evaluated its regulatory mechanism. TBG inhibi...

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Detalles Bibliográficos
Autores principales: Gao, Yuxue, Shi, Lihong, Cao, Zhen, Zhu, Xuetao, Li, Feng, Wang, Ruyan, Xu, Jinyuan, Zhong, Jinyi, Zhang, Baogang, Lu, Shijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920466/
https://www.ncbi.nlm.nih.gov/pubmed/29725474
http://dx.doi.org/10.3892/ol.2018.8349