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Downregulation of SM22α protein by hypermethylation of its promoter in colorectal cancer
Silencing of tumor suppressor genes by hypermethylation in gene promoter regions is a crucial mechanism in carcinogenesis. Gene methylation may be reversible and evaluated easily, thus providing a promising substrate for the development of biomarkers for the detection and prevention of cancer, inclu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920476/ https://www.ncbi.nlm.nih.gov/pubmed/29725466 http://dx.doi.org/10.3892/ol.2018.8350 |