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Downregulation of SM22α protein by hypermethylation of its promoter in colorectal cancer

Silencing of tumor suppressor genes by hypermethylation in gene promoter regions is a crucial mechanism in carcinogenesis. Gene methylation may be reversible and evaluated easily, thus providing a promising substrate for the development of biomarkers for the detection and prevention of cancer, inclu...

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Detalles Bibliográficos
Autores principales: Liu, Yabin, Wei, Erqiang, Zhao, Jian, Kong, Dexian, Li, Binghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920476/
https://www.ncbi.nlm.nih.gov/pubmed/29725466
http://dx.doi.org/10.3892/ol.2018.8350

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