EGFR and HER2 Activate Rigidity Sensing Only on Rigid Matrices

Epidermal growth factor receptor (EGFR) interacts with integrins during cell spreading and motility, but little is known about the role of EGFR in these mechanosensing processes. Here we show, using two different cell lines, that in serum- and EGF-free conditions, EGFR or HER2 activity increase spre...

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Detalles Bibliográficos
Autores principales: Saxena, Mayur, Liu, Shuaimin, Yang, Bo, Hajal, Cynthia, Changede, Rishita, Hu, Junqiang, Wolfenson, Haguy, Hone, James, Sheetz, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920513/
https://www.ncbi.nlm.nih.gov/pubmed/28459445
http://dx.doi.org/10.1038/nmat4893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920513/
https://www.ncbi.nlm.nih.gov/pubmed/28459445
http://dx.doi.org/10.1038/nmat4893

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