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EGFR and HER2 Activate Rigidity Sensing Only on Rigid Matrices
Epidermal growth factor receptor (EGFR) interacts with integrins during cell spreading and motility, but little is known about the role of EGFR in these mechanosensing processes. Here we show, using two different cell lines, that in serum- and EGF-free conditions, EGFR or HER2 activity increase spre...
Autores principales: | Saxena, Mayur, Liu, Shuaimin, Yang, Bo, Hajal, Cynthia, Changede, Rishita, Hu, Junqiang, Wolfenson, Haguy, Hone, James, Sheetz, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920513/ https://www.ncbi.nlm.nih.gov/pubmed/28459445 http://dx.doi.org/10.1038/nmat4893 |
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