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Extra-Large Pore Mesoporous Silica Nanoparticles Enabling Co-Delivery of High Amounts of Protein Antigen and Toll-like Receptor 9 Agonist for Enhanced Cancer Vaccine Efficacy

[Image: see text] Cancer vaccine aims to invoke antitumor adaptive immune responses to detect and eliminate tumors. However, the current dendritic cells (DCs)-based cancer vaccines have several limitations that are mostly derived from the ex vivo culture of patient DCs. To circumvent the limitations...

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Detalles Bibliográficos
Autores principales: Cha, Bong Geun, Jeong, Ji Hoon, Kim, Jaeyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920615/
https://www.ncbi.nlm.nih.gov/pubmed/29721531
http://dx.doi.org/10.1021/acscentsci.8b00035