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Inhibition of 1,2‐Dimethylhydrazine‐induced Oxidative DNA Damage by Green Tea Extract in Rat

Following subcutaneous injection of 1,2‐dimethylhydrazine (DMH), which is carcinogenic to rat colon and liver, to Sprague‐Dawley rats, a significant increase of 8‐hydroxydeoxyguanosine (8‐OHdG) was observed in the DNA of colonic mucosa and liver. The 8‐OHdG formation reached the maximal level at abo...

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Detalles Bibliográficos
Autores principales: Inagake, Masao, Yamane, Tetsuro, Kitao, Yoshitaka, Oya, Kazuhiko, Matsuraoto, Hirohiko, Kikuoka, Norikazu, Nakatani, Hirohisa, Takahashi, Toshio, Nishimura, Hiroshi, Iwashiraa, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920630/
https://www.ncbi.nlm.nih.gov/pubmed/8567403
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03027.x