Infectious Retrovirus Is Inactivated by Serum but Not by Cerebrospinal Fluid or Fluid from Tumor Bed in Patients with Malignant Glioma

Intravenous gene transfer using recombinant retroviruses tends to suffer from a low infectious viral titer when conducted in vivo. This is, in part, caused by complement‐mediated proteolytic inactivation of the retrovirus in human serum. However, if the retroviruses were directly injected into the b...

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Detalles Bibliográficos
Autores principales: Shimizu, Keiji, Miyao, Yasuyoshi, Tamura, Masakazu, Kishima, Haruhiko, Ohkawa, Motohisa, Mabuchi, Eiichiro, Yamada, Masanobu, Hayakawa, Toru, Ikenaka, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920638/
https://www.ncbi.nlm.nih.gov/pubmed/8567389
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03013.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920638/
https://www.ncbi.nlm.nih.gov/pubmed/8567389
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03013.x

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