Absence of ras Mutations and Low Incidence of p53 Mutations in Renal Cell Carcinomas Induced by Ferric Nitrilotriacetate

Renal cell carcinomas induced in male Wistar rats by iron chelate of nitrilotriacetate (Fe‐NTA) were examined for mutations in ras oncogenes and p53 tumor suppressor gene. Fourteen primary tumors and two metastatic tumors from 11 animals were evaluated. Exons 1 and 2 of the H‐, K‐, and N‐ras genes w...

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Detalles Bibliográficos
Autores principales: Akiyama, Takashi, Hamazaki, Shuji, Okada, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920661/
https://www.ncbi.nlm.nih.gov/pubmed/8636002
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03307.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920661/
https://www.ncbi.nlm.nih.gov/pubmed/8636002
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03307.x

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