Phase I Study of Paclitaxel by Three‐hour Infusion: Hypotension Just after Infusion Is One of the Major Dose‐limiting Toxicities

The primary objectives of this study were to determine the maximum tolerated dose (MTD) of paclitaxel administered by 3‐h infusion to patients with solid tumors, and to characterize the pharmacokinetics of a 3‐h infusion in comparison with those of a 24‐h infusion. Twenty‐seven patients each receive...

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Detalles Bibliográficos
Autores principales: Tamura, Tomohide, Sasaki, Yasutsuna, Nishiwaki, Yutaka, Saijo, Nagahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920663/
https://www.ncbi.nlm.nih.gov/pubmed/8636011
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03316.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920663/
https://www.ncbi.nlm.nih.gov/pubmed/8636011
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03316.x

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