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Induction of DNA Recombination by Activated 3‐Amino‐1‐methyl‐5H‐pyrido[4,3‐b]indole

To investigate the genotoxic properties of a food‐derived carcinogen, 3‐amino‐1‐methyl‐5H‐pyrido‐[4,3‐b]indole (Trp‐P‐2), we have tested whether Trp‐P‐2 and its metabolically transformed products can induce DNA recombinations. Trp‐P‐2 is a strong mutagen and its activated form, the N‐hydroxylated de...

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Detalles Bibliográficos
Autores principales: Hiramoto, Kazuyuki, Kanamitsu, Shin‐ichi, Negishi, Kazuo, Ikeda, Hideo, Hayatsu, Hikoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920750/
https://www.ncbi.nlm.nih.gov/pubmed/7730138
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03033.x