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Comparison of Incorporation and Extension of Nucleotides in vitro opposite 8‐Hydroxyguanine (7,8‐Dihydro‐8‐oxoguanine) in Hot Spots of the c‐Ha‐ras Gene

DNA templates with 8‐hydroxyguanine (7,8‐dihydro‐8‐oxoguanine, oh(8)Gua) at a site corresponding to the first or second position of codon 12 of the c‐Ha‐ras gene were prepared, and the nucleotides inserted opposite the modified base were compared. The Klenow fragment (KF) of Escherichia coli DNA pol...

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Detalles Bibliográficos
Autores principales: Kamiya, Hiroyuki, Murata‐Kamiya, Naoko, Fujimuro, Masahiro, Kido, Kaori, Inoue, Hideo, Nishimura, Susumu, Masutani, Chikahide, Hanaoka, Fumio, Ohtsuka, Eiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920815/
https://www.ncbi.nlm.nih.gov/pubmed/7744697
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03050.x