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Inhibition of Tumor‐induced Angiogenesis by a Synthetic Lipid A Analogue with Low Endotoxicity, DT‐5461

We investigated the effect of a synthetic lipid A analogue with low endotoxicity, DT‐5461, on the neovascularization induced by B16‐BL6 melanoma in syngenelc mice. A systemic single administration of DT‐5461 caused a marked decrease in the number of vessels oriented toward the tumor mass and in the...

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Detalles Bibliográficos
Autores principales: Sato, Katsuaki, Yoo, Yung Choon, Mochizuki, Mami, Saiki, Ikuo, Takahashi, Tsuneo A., Azuma, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920831/
https://www.ncbi.nlm.nih.gov/pubmed/7539783
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03067.x