Direct Transplantation of Chronic Myelogenous Leukemia Cells into Nude Mice and Establishment of a Leukemic Stem Cell (Ph(1+), CD34(+)) Line Dependent on Mouse Bone Marrow Stromal Cells in vitro

Peripheral blood cells from a female patient with Ph(1)‐positive chronic myelogenous leukemia (CML) in blast crisis were serially transplanted in BALB/c nude mice for 16 passages. This in vivo cell line, designated CML‐N‐1, had Ph(1)chromosome abnormality and BCR gene rearrangement. The cells expres...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubonishi, Ichiro, Takeuchi, Seisho, Uemura, Yoshiki, Kamioka, Mikio, Asahi, Yasutomo, Ohtsuki, Yuji, Miyoshi, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920846/
https://www.ncbi.nlm.nih.gov/pubmed/7540608
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03078.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920846/
https://www.ncbi.nlm.nih.gov/pubmed/7540608
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03078.x

Ejemplares similares