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New Flow Cytometric Method for Detection of Minimally Expressed Multidrug Resistance P‐Glycoprotein on Normal and Acute Leukemia Cells Using Biotinylated MRK16 and Streptavidin‐RED670 Conjugate

To evaluate the expression of multidrug resistance (MDR) on normal and leukemia cells, we examined P‐glycoprotein (P‐gp) by a newly devised flow cytometric method, utilizing a biotinylated monoclonal antibody (mAb) against P‐gp (MRK16), a streptavidin‐RED670 conjugate (SA‐RED670) and appropriate emi...

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Detalles Bibliográficos
Autores principales: Takeshita, Akihiro, Shinjo, Kaori, Ohnishl, Kazunori, Ohno, Ryuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920863/
https://www.ncbi.nlm.nih.gov/pubmed/7622426
http://dx.doi.org/10.1111/j.1349-7006.1995.tb02441.x