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Analysis of human MutS homolog 2 missense mutations in patients with colorectal cancer

Germline mutations of DNA mismatch repair gene human MutS homolog 2 (hMSH2) are associated with hereditary nonpolyposis colorectal cancer (HNPCC). A total of one-third of these mutations are missense mutations. Several hMSH2 missense mutations have been identified in patients in East Asia, although...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaomei, Chen, Senqing, Yu, Jun, Zhang, Yuanying, Lv, Min, Zhu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920917/
https://www.ncbi.nlm.nih.gov/pubmed/29731845
http://dx.doi.org/10.3892/ol.2018.8161