Inhibition of p53 Protein Phosphorylation by 9‐Hydroxyellipticine: A Possible Anticancer Mechanism

Abnormality of p53, a tumor suppressor gene, is considered to be a potential cause of malignancy. We found that ellipticine and 9‐hydroxyellipticine (9HE), antitumor alkaloids, caused selective inhibition of p53 protein phospborylation in Lewis lung carcinoma and SW480 (human colon cancer cell line)...

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Detalles Bibliográficos
Autores principales: Ohashi, Motoaki, Sugikawa, Emiko, Nakanishi, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1995
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920929/
https://www.ncbi.nlm.nih.gov/pubmed/7591958
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03091.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920929/
https://www.ncbi.nlm.nih.gov/pubmed/7591958
http://dx.doi.org/10.1111/j.1349-7006.1995.tb03091.x

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