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Hepatocellular Carcinoma Induction in LEC Rats by a Low Dose of 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline

A food‐borne heterocyclic amine, 2‐amino‐3,8‐dimethylimidazo[4,5‐f]qninoxaline (MeIQx), induces hepatocellular carcinomas (HCCs) in F344 male rats at an incidence of 95%, when fed in the diet at 400 ppm for 61 weeks. In this study, the effect of a low dose of MeIQx was examined in Long‐Evans with ci...

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Detalles Bibliográficos
Autores principales: Sone, Hideko, Wakabayashi, Keiji, Kushida, Hiromi, Enomoto, Katsuhiko, Mori, Michio, Takeichi, Noritoshi, Tsuda, Hiroyuki, Sugimura, Takashi, Nagao, Minako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920977/
https://www.ncbi.nlm.nih.gov/pubmed/8609044
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00195.x