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Comparison of in vivo Efficacy of Hypoxic Cytotoxin Tirapazamine and Hypoxic Cell Radiosensitizer KU‐2285 in Combination with Single and Fractionated Irradiation

Development of strategies to eradicate radioresistant hypoxic cells would be of great benefit for clinical radiotherapy. In the present study, the in vivo effects of a promising hypoxic cytotoxin, tirapazamine (3‐amino‐1,2,4‐benzotriazine 1,4‐di‐N‐oxide), were examined in comparison with those of KU...

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Detalles Bibliográficos
Autores principales: Shibata, Toru, Shibamoto, Yuta, Sasai, Keisuke, Oya, Natsuo, Murata, Rumi, Takagi, Takehisa, Hiraoka, Masahiro, Abe, Mitsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920986/
https://www.ncbi.nlm.nih.gov/pubmed/8609056
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00206.x