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Dose‐dependent Induction of Mammary Carcinomas in Female Sprague‐Dawley Rats with 2‐Amino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridine

The dose‐dependence of 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) induction of mammary carcinomas was investigated in female Sprague‐Dawley (SD) rats given PhIP in the diet for 48 weeks at concentrations of 0, 25, 100 and 200 ppm in experiment 1, and 0, 12.5, 50 in experiment 2. Yields o...

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Detalles Bibliográficos
Autores principales: Imaida, Katsumi, Hagiwara, Akihiro, Yada, Hideaki, Masui, Tsuneo, Hasegawa, Ryohei, Hirose, Masao, Sugimura, Takashi, Ito, Nobuyuki, Shirai, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921009/
https://www.ncbi.nlm.nih.gov/pubmed/9045939
http://dx.doi.org/10.1111/j.1349-7006.1996.tb03120.x