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Dose‐dependent Induction of Mammary Carcinomas in Female Sprague‐Dawley Rats with 2‐Amino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridine
The dose‐dependence of 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) induction of mammary carcinomas was investigated in female Sprague‐Dawley (SD) rats given PhIP in the diet for 48 weeks at concentrations of 0, 25, 100 and 200 ppm in experiment 1, and 0, 12.5, 50 in experiment 2. Yields o...
Autores principales: | Imaida, Katsumi, Hagiwara, Akihiro, Yada, Hideaki, Masui, Tsuneo, Hasegawa, Ryohei, Hirose, Masao, Sugimura, Takashi, Ito, Nobuyuki, Shirai, Tomoyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921009/ https://www.ncbi.nlm.nih.gov/pubmed/9045939 http://dx.doi.org/10.1111/j.1349-7006.1996.tb03120.x |
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