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Failure to Detect Mutations in the Retinoblastoma Protein‐binding Domain of the Transcription Factor E2F‐1 in Human Cancers

The functions of the transcription factor E2F‐1 are regulated by the RB protein through the RB‐binding domain of E2F‐1 and this factor is considered to be an important molecule that functions downstream of the RB protein. In order to determine whether E2F‐1 that cannot bind to RB might be associated...

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Detalles Bibliográficos
Autores principales: Nakamura, Takao, Monden, Yoshiaki, Kawashima, Kazuko, Naruke, Tsuguo, Nishimura, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921028/
https://www.ncbi.nlm.nih.gov/pubmed/9045954
http://dx.doi.org/10.1111/j.1349-7006.1996.tb03134.x