Reduced Activity of Anabolizing Enzymes in 5‐Fluorouracil‐resistant Human Stomach Cancer Cells

The mechanism of resistance to 5‐fluorouracil (5‐FU) was studied with NUGC‐3/5FU/L, a human stomach cancer cell line which had acquired resistance as a consequence of repeated 5‐day exposures to stepwise‐increasing concentrations of 5‐FU in vitro. NUGC‐3/5FU/L was 200‐fold and over 16‐fold resistant...

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Detalles Bibliográficos
Autores principales: Inaba, Makoto, Mitsuhashi, Junko, Sawada, Hiroko, Miike, Naoko, Naoe, Yoshinori, Daimon, Aiko, Koizumi, Kazuhisa, Tsujimoto, Hiroaki, Fukushima, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921054/
https://www.ncbi.nlm.nih.gov/pubmed/8609072
http://dx.doi.org/10.1111/j.1349-7006.1996.tb03161.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921054/
https://www.ncbi.nlm.nih.gov/pubmed/8609072
http://dx.doi.org/10.1111/j.1349-7006.1996.tb03161.x

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