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Reduced Activity of Anabolizing Enzymes in 5‐Fluorouracil‐resistant Human Stomach Cancer Cells
The mechanism of resistance to 5‐fluorouracil (5‐FU) was studied with NUGC‐3/5FU/L, a human stomach cancer cell line which had acquired resistance as a consequence of repeated 5‐day exposures to stepwise‐increasing concentrations of 5‐FU in vitro. NUGC‐3/5FU/L was 200‐fold and over 16‐fold resistant...
Autores principales: | Inaba, Makoto, Mitsuhashi, Junko, Sawada, Hiroko, Miike, Naoko, Naoe, Yoshinori, Daimon, Aiko, Koizumi, Kazuhisa, Tsujimoto, Hiroaki, Fukushima, Masakazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921054/ https://www.ncbi.nlm.nih.gov/pubmed/8609072 http://dx.doi.org/10.1111/j.1349-7006.1996.tb03161.x |
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