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Absence of a Mutation of the p21/WAF1 Gene in Human Lung and Pancreatic Cancers
The expression of a negative regulator of the cell cycle, p21(WAF1) protein, is trans‐activated hy wild‐type p53, but not by the mutant protein. Therefore, mutations of the p53 and WAF1 genes may be complementary. We examined DNAs from 70 human primary lung (63 of NSCLC and 7 of SCLC) and 24 pancrea...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921085/ https://www.ncbi.nlm.nih.gov/pubmed/8613430 http://dx.doi.org/10.1111/j.1349-7006.1996.tb00217.x |