Absence of a Mutation of the p21/WAF1 Gene in Human Lung and Pancreatic Cancers

The expression of a negative regulator of the cell cycle, p21(WAF1) protein, is trans‐activated hy wild‐type p53, but not by the mutant protein. Therefore, mutations of the p53 and WAF1 genes may be complementary. We examined DNAs from 70 human primary lung (63 of NSCLC and 7 of SCLC) and 24 pancrea...

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Detalles Bibliográficos
Autores principales: Shimizu, Tatsunori, Miwa, Wataru, Nakamori, Shoji, Ishikawa, Osamu, Konishi, Yoichi, Sekiya, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921085/
https://www.ncbi.nlm.nih.gov/pubmed/8613430
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00217.x

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