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Inhibition of Cell Growth by Transforming Growth Factor β1 Is Associated with p53‐Independent Induction of p21 in Gastric Carcinoma Cells

Cell cycle regulators such as cyclins, cyclin‐dependent kinases (cdks) and their inhibitors control the growth of cells. SDI1/CIP1/WAF1/p21 is a potent inhibitor of G1 cdks, whose expression is induced by wild‐type p53. To elucidate the mechanism of growth inhibition by transforming growth factor β1...

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Detalles Bibliográficos
Autores principales: Akagi, Morihisa, Yasui, Wataru, Akama, Yoshihiko, Yokozaki, Hiroshi, Tahara, Hidetoshi, Haruma, Ken, Kajiyama, Goro, Tahara, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921106/
https://www.ncbi.nlm.nih.gov/pubmed/8641969
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00233.x