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Selective Reduction in α‐Hydroxypalmitic Acid‐containing Sphingomyelin and Concurrent Increase in Hydroxylated Ceramides in Murine Skin Tumors Induced by an Initiation‐promotion Regimen

The sphingomyelin cycle is activated to accumulate ceramides in the process of epidermal differentiation. We found that sphingomyelin in the epidermis of 4 different murine strains gave three bands on TLC, the lower band containing α‐hydroxypalmitic acid (C16h:0(α)). However, in the papillomas induc...

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Detalles Bibliográficos
Autores principales: Kitano, Yukie, Iwamori, Yuriko, Kiguchi, Kaoru, DiGiovanni, John, Takahashi, Toshie, Kasama, Kenji, Niwa, Takashi, Harii, Kiyonori, Iwamori, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921126/
https://www.ncbi.nlm.nih.gov/pubmed/8641979
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00243.x