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Selective Reduction in α‐Hydroxypalmitic Acid‐containing Sphingomyelin and Concurrent Increase in Hydroxylated Ceramides in Murine Skin Tumors Induced by an Initiation‐promotion Regimen
The sphingomyelin cycle is activated to accumulate ceramides in the process of epidermal differentiation. We found that sphingomyelin in the epidermis of 4 different murine strains gave three bands on TLC, the lower band containing α‐hydroxypalmitic acid (C16h:0(α)). However, in the papillomas induc...
Autores principales: | Kitano, Yukie, Iwamori, Yuriko, Kiguchi, Kaoru, DiGiovanni, John, Takahashi, Toshie, Kasama, Kenji, Niwa, Takashi, Harii, Kiyonori, Iwamori, Masao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921126/ https://www.ncbi.nlm.nih.gov/pubmed/8641979 http://dx.doi.org/10.1111/j.1349-7006.1996.tb00243.x |
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