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Oncogenic Collaboration of the Cyclin D1 (PRAD1, bcl‐1) Gene with a Mutated p53 and an Activated ras Oncogene in Neoplastic Transformation

Cyclin D1 is one of the key regulators in G1 progression in the cell cycle and is also a candidate oncogene (termed PRAD1 or bcl‐1) in several types of human tumors. We report a collaboration of the cyclin D1 gene with ras and a mutated form of p53 (p53‐mt) in neoplastic transformation. Transfection...

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Detalles Bibliográficos
Autores principales: Uchimaru, Kaoru, Endo, Koichi, Fujinuma, Haruko, Zukerberg, Lawrence, Arnold, Andrew, Motokura, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921129/
https://www.ncbi.nlm.nih.gov/pubmed/8641982
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00246.x